INTRODUCTION TO PHARMACOKINETICS AND BARRIER MEMBRANES
Perhaps, If Tom would have known what's in there and what does it do to him he would not have been this much afraid of the situation.😕
We all would have faced the same fearful situation 😫 when we were young👶, even we did not know at that time what PHARMACOKINETICS really is and how we are overcoming sickness😊!!!
PHARMACOKINETICS is defined as the process of how drug concentrations changes with time in one or more different regions of the body in relation to dosing
For a drug to be utilized in the body it has to overcome various barriers before reaching the target of action.. Mechanisms by which a drug cross these barriers along with their physicochemical properties also play a major role in their movement.
Source: John Wiley & Sons.Inc |
The fluid compartments of the body are divided into Intracellular and extracellular fluids. The extracellular fluid is further composed of 80% Interstitial fluid and 20% plasma. These compartments are seperated by barrier membranes namely the capillary membrane and the cell membrane. Interstitial fluid is present between these two membranes.
source:https://uomustansiriyah.edu.iq/media/lectures/2/2_2017_03_20!09_59_09_AM.pdf |
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